Searchable, peer-reviewed, open-access proceedings from bioscience and biomedical conferences

bp0003rdr3 | Maternal-Embryo Interactions | REDR1994

Matrix metalloproteinases and their tissue inhibitors at the ovine trophoblast-uterine interface

Salamonsen LA , Nagase H , Woolley DE

Trophoblast invasiveness in ruminants is limited to fusion of migrating binucleate cells with uterine epithelium, but considerable tissue remodelling and angiogenesis occurs within the endometrium at implantation. Such processes are elsewhere associated with an altered balance of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs). ProMMPs-1, -2, -3 are secreted by cultured ovine endometrial stromal, but not epithelial, cells and expression of proMMP-1 and pro...

bp0019cpr3 | Gametes and Embryos | CPR2013

Boar seminal plasma proteins and their relevance to reproductive technologies

W.L. Flowers1, K.R. Stewart1, T. Gall2, S. Novak3, M.K. Dyck3 , and R.N. Kirkwood4 , Nagase H , Woolley DE

Seminal plasma proteins participate in a number of events important for fertilization and the establishment of pregnancy. As a result, attempts have been made to use them to enhance reproductive performance associated with several swine reproductive technologies. Inclusion of seminal plasma into cryopreservation and sex-sorting protocols improved sperm viability and membrane integrity and suppressed capacitation-like changes which are considered to be major challenges as...